GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6050555 | chr20:25328543 | ENTPD6 | chr20:25176339-25207360:+ | 0.31 | 6.91 | 1.58E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050555 | chr20:25328543 | FAM182B | chr20:25744102-25848786:- | -0.27 | -5.52 | 5.71E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050555 | chr20:25328543 | NINL | chr20:25433338-25566153:- | 0.34 | 6.95 | 1.2E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050555 | chr20:25328543 | PYGB | chr20:25228706-25278647:+ | 0.17 | 4.15 | 3.9E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050559 | chr20:25329915 | ENTPD6 | chr20:25176339-25207360:+ | -0.29 | -6.57 | 1.32E-10 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050559 | chr20:25329915 | FAM182A | chr20:26035250-26067552:+ | -0.19 | -3.45 | 0.000602 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050559 | chr20:25329915 | FAM182B | chr20:25744102-25848786:- | 0.26 | 5.49 | 6.49E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050559 | chr20:25329915 | NINL | chr20:25433338-25566153:- | -0.35 | -7.23 | 1.88E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050559 | chr20:25329915 | PYGB | chr20:25228706-25278647:+ | -0.14 | -3.64 | 0.000306 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050561 | chr20:25334855 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.84E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050561 | chr20:25334855 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000539 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050561 | chr20:25334855 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.08E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050561 | chr20:25334855 | NINL | chr20:25433338-25566153:- | 0.33 | 6.89 | 1.74E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050561 | chr20:25334855 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.46E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050562 | chr20:25336186 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.7 | 5.92E-11 | Liver enzyme levels (alkaline phosphatase) |